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ALK-IN-1

Cat. No.:YN440273

  • CAS No. :1197958-12-5

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    • 产品名称: ALK-IN-1
      CAS No.: 1197958-12-5
      Chemical Name: 5-chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine
      Synonyms:Brigatinib analog
      分子量:529.01
      分子式:C₂₆H₃₄ClN₆O₂P
      SMILES:CP(C)(C1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCC(N(C)C)CC4)C=C3OC)=NC=C2Cl)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: ALK-IN-1 (Brigatinib analog) 是ALK激酶高效选择性抑制剂,出自专利 US20140066406 A1。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Huang, W.S., Liu, S., Zou, D., et al.Discovery of brigatinib (AP26113), a phosphine oxide-containing, potent, orally active inhibitor of anaplastic lymphoma kinaseJ. Med. Chem.,(2016)

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