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ZD 7155(hydrochloride)

Cat. No.:YN320220

  • CAS No. :146709-78-6

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    • 产品名称: ZD 7155(hydrochloride)
      CAS No.: 146709-78-6
      Chemical Name: 5,7-diethyl-3,4-dihydro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,6-naphthyridin-2(1H)-one, monohydrochloride
      Synonyms:
      分子量:474.99
      分子式:C₂₆H₂₇ClN₆O
      SMILES:O=C1CCC2=C(C=C(CC)N=C2CC)N1CC(C=C3)=CC=C3C4=CC=CC=C4C5=NN=NN5.[H]Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: ZD 7155 hydrochloride是血管紧张素II受体1型 (AT1 receptor) 拮抗剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Zhang, H., Unal, H., Gati, C., et al.Structure of the Angiotensin receptor revealed by serial femtosecond crystallographyCell161(4),833-844(2015)

      Junggren, I.L., Zhao, X., Sun, X., et al.Comparative cardiovascular effects of the angiotensin II type 1 receptor antagonists ZD 7155 and losartan in the ratJ. Pharm. Pharmacol.48(8),829-833(1996)

      Maxfield, E.K., Love, A., Cotter, M.A., et al.Nerve function and regeneration in diabetic rats: Effects of ZD-7155, an AT1 receptor antagonistAm. J. Physiol.269(3 Pt 1),E530-537(1995)

      Wang, F., Xia, Z.-F., Chen, X.-L., et al.Angiotensin II type-1 receptor antagonist attenuates LPS-induced acute lung injuryCytokine48(3),246-253(2009)

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