Tasosartan
Cat. No.：YN321361
CAS No. ：145733-36-4
| 产品名称: | Tasosartan |
| CAS No.: | 145733-36-4 |
| Chemical Name: | 5,8-dihydro-2,4-dimethyl-8-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-pyrido[2,3-d]pyrimidin-7(6H)-one |
| Synonyms: | WAY-ANA 756 |
| 分子量: | 411.46 |
| 分子式: | C₂₃H₂₁N₇O |
| SMILES: | O=C1CCC2=C(C)N=C(C)N=C2N1CC3=CC=C(C4=CC=CC=C4C5=NNN=N5)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tasosartan 是一种长效的血管紧张素 II (AngII) 受体拮抗剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Ellingboe, J.W., Collini, M.D., Quagliato, D., et al.Metabolites of the angiotensin II antagonist tasosartan: The importance of a second acidic groupJ. Med. Chem.41(22),4251-4260(1998)
Hines, J., Fluharty, S.J., and Sakai, R.R.The angiotensin AT1 receptor antagonist irbesartan has near-peptide affinity and potently blocks receptor signalingEur. J. Pharmacol.384(1),81-89(1999)
Ellingboe, J.W., Antane, M., Nguyen, T.T., et al.Pyrido[2,3-d]pyrimidine angiotensin II antagonistsJ. Med. Chem.37(4),542-550(1994)
