Irbesartan D4
Cat. No.：YN321425
| 产品名称: | Irbesartan D4 |
| CAS No.: | 1216883-23-6 |
| Chemical Name: | 3-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one |
| Synonyms: | 厄贝沙坦 D4; SR-47436 D4; BMS-186295 D4 |
| 分子量: | 432.55 |
| 分子式: | C₂₅H₂₄D₄N₆O |
| SMILES: | O=C1N(CC2=C([2H])C([2H])=C(C3=C(C4=NN=NN4)C=CC=C3)C([2H])=C2[2H])C(CCCC)=NC15CCCC5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Irbesartan D4 是 Irbesartan 的氘代物。 |
| IC50和靶点: | |
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Burnier, M.Angiotensin II type 1 receptor blockersCirculation103(6),904-912(2001)
Gradman, A.H.AT1-receptor blockers: Differences that matterJ. Hum. Hypertens.16,S9-S16(2002)
Shimamura, T., Masui, M., Torii, M., et al.Hypotensive and prophylactic effects of angiotensin II subtype 1 receptor antagonist, irbesartan, in stroke-prone spontaneously hypertensive ratsClin. Exp. Hypertens.26(1),27-42(2004)
Candido, R., Allen, T.J., Lassila, M., et al.Irbesartan but not amlodipine suppresses diabetes-associated atherosclerosisCirculation109(12),1536-1542(2004)
