Eprosartan mesylate
Cat. No.:YN321036
CAS No. :144143-96-4
产品名称: | Eprosartan mesylate |
CAS No.: | 144143-96-4 |
Chemical Name: | (αE)-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-2-thiophenepropanoic acid, mesylate |
Synonyms: | SKF-108566J |
分子量: | 520.62 |
分子式: | C₂₄H₂₈N₂O₇S₂ |
SMILES: | OC(/C(CC1=CC=CS1)=C/C2=CN=C(CCCC)N2CC3=CC=C(C(O)=O)C=C3)=O.CS(=O)(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Eprosartan mesylate (SKF-108566J) 是非肽类血管紧张素II受体拮抗剂,在鼠和人肾上腺皮质膜中的IC50分别为9.2和3.9 nM。 |
IC50和靶点: | |
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Blankestijn, P.J., and Rupp, H.Clinical profile of eprosartan: A different angiotensin II receptor blockerCardiovasc. Hematol. Agents Med. Chem.6(4),253-257(2008)
Burnier, M.Angiotensin II type 1 receptor blockersCirculation103(6),904-912(2001)