Olmesartan
Cat. No.：YN321101
CAS No. ：144689-24-7
| 产品名称: | Olmesartan |
| CAS No.: | 144689-24-7 |
| Chemical Name: | 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid |
| Synonyms: | 奥美沙坦; RNH-6270 |
| 分子量: | 446.50 |
| 分子式: | C₂₄H₂₆N₆O₃ |
| SMILES: | O=C(O)C1=C(N=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=NN4)CCC)C(O)(C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Olmesartan (RNH-6270) 是血管紧张素II受体 (AT1R) 拮抗剂，常用于高血压的相关研究。 |
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Mizuno, M., Sada, T., Ikeda, M., et al.Pharmacology of CS-866, a novel nonpeptide angiotensin II receptor antagonistEur. J. Pharmacol.285(2),181-188(1995)
Ishizuka, T., Fujimori, I., Nishida, A., et al.Paraoxonase 1 as a major bioactivating hydrolase for olmesartan medoxomil in human blood circulation: Molecular identification and contribution to plasma metabolismDrug Metab. Dispos.40(2),374-380(2012)
