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Veliparib dihydrochloride

Cat. No.：912445-05-7

  • CAS No. ：912445-05-7

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    • 产品名称: Veliparib dihydrochloride
      CAS No.: 912445-05-7
      Chemical Name:
      Synonyms:维利帕尼二盐酸盐; ABT-888 dihydrochloride
      分子量:317.21
      分子式:C₁₃H₁₈Cl₂N₄O
      SMILES:O=C(C1=C2NC([C@@]3(NCCC3)C)=NC2=CC=C1)N.Cl.Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Davar, D., Beumer, J.H., Hamieh, L., et al.Role of PARP inhibitors in cancer biology and therapyCurr. Med. Chem.19(23),3907-3921(2012)', 'Javle, M., and Curtin, N.J.The potential for poly (ADP-ribose) polymerase inhibitors in cancer therapyTher. Adv. Med. Oncol.3(6),257-267(2011)', 'Donawho, C.K., Luo, Y., Penning, T.D., et al.ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor modelsClin. Cancer Res.13(9),2728-2737(2007)', 'Albert, J.M., Cao, C., Kim, K.W., et al.Inhibition of poly(ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer modelsClin. Cancer Res.13(10),3033-3042(2007)', 'Liu, X., Luo, X., Shi, Y., et al.Poly (ADP-ribose) polymerase activity regulates apoptosis in HeLa cells after alkylating DNA damageCancer Biol. Ther.7(6),934-941(2008)', 'Shelton, J.W., Waxweiler, T.V., Landry, J., et al.In vitro and in vivo enhancement of chemoradiation using the oral PARP inhibitor ABT-888 in colorectal cancer cellsInt. J. Radiat. Oncol. Biol. Phys.86(3),469-476(2013)', 'Shunkwiler, L., Ferris, G., and Kunos, C.Inhibition of poly(ADP-ribose) polymerase enhances radiochemosensitivity in cancers proficient in DNA double-strand break repairInt. J. Mol. Sci.14(2),3773-3785(2013)
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    摩尔浓度计算器方程 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    质量 浓度 体积 分子量
    稀释计算器 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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