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Danusertib

Cat. No.：827318-97-8

  • CAS No. ：827318-97-8

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    • 产品名称: Danusertib
      CAS No.: 827318-97-8
      Chemical Name:
      Synonyms:PHA-739358
      分子量:474.55
      分子式:C₂₆H₃₀N₆O₃
      SMILES:O=C(N1CC2=C(NN=C2NC(C3=CC=C(N4CCN(CC4)C)C=C3)=O)C1)[C@@H](C5=CC=CC=C5)OC
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Carpinelli, P., Ceruti, R., Giorgini, M.L., et al.PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancerMol. Cancer Ther.6(12 Pt 1),3158-3153(2007)', 'Gontarewicz, A., Balabanov, S., Keller, G., et al.Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315IBlood111(8),4355-4364(2008)', 'Moore, A.S., Blagg, J., Linardopoulos, S., et al.Aurora kinase inhibitors: Novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemiasLeukemia24(4),671-678(2010)
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