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Milciclib

Cat. No.：802539-81-7

  • CAS No. ：802539-81-7

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    • 产品名称: Milciclib
      CAS No.: 802539-81-7
      Chemical Name:
      Synonyms:PHA-848125
      分子量:460.57
      分子式:C₂₅H₃₂N₈O
      SMILES:O=C(NC)C1=NN(C2=C1C(C)(CC3=CN=C(N=C23)NC4=CC=C(C=C4)N5CCN(CC5)C)C)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Brasca, M.G., Amboldi, N., Ballinari, D., et al.Identification of N,1,4,4-tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (PHA-848125), a potent, orally available cyclin dependent kinase inhibitorJ. Med. Chem.52(16),5152-5163(2009)', 'Caporali, S., Alvino, E., Starace, G., et al.The cyclin-dependent kinase inhibitor PHA-848125 suppresses the in vitro growth of human melanomas sensitive or resistant to temozolomide, and shows synergistic effects in combination with this triazene compoundPharmacol. Res.61(5),437-448(2010)', 'Degrassi, A., Russo, M., Nanni, C., et al.Efficacy of PHA-848125, a cyclin-dependent kinase inhibitor, on the K-RasG12DLA2 lung adenocarcinoma transgenic mouse model: Evaluation by multimodality imagingMol. Cancer Ther.9(3),673-681(2010)
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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    稀释计算器 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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