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GSK2578215A

Cat. No.：1285515-21-0

  • CAS No. ：1285515-21-0

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    • 产品名称: GSK2578215A
      CAS No.: 1285515-21-0
      Chemical Name:
      Synonyms:5-(2-氟-4-吡啶基)-2-(苯基甲氧基)-N-3-吡啶基苯甲酰胺
      分子量:399.42
      分子式:C₂₄H₁₈FN₃O₂
      SMILES:FC1=NC=CC(C2=CC(C(NC3=CC=CN=C3)=O)=C(OCC4=CC=CC=C4)C=C2)=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Reith, A.D., Bamborough, P., Jandu, K., et al.GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitorBioorg. Med. Chem. Lett.22(17),5625-5629(2012)', 'Saez-Atienzar, S., Bonet-Ponce, L., Blesa, J.R., et al.The LRRK2 inhibitor GSK2578215A induces protective autophagy in SH-SY5Y cells: Involvement of Drp-1-mediated mitochondrial fission and mitochondrial-derived ROS signalingCell Death Dis.14(5),e1368(2014)', 'Yan, J., Almilaji, A., Schmid, E., et al.Leucine-rich repeat kinase 2-sensitive Na+/Ca2+ exchanger activity in dendritic cellsFASEB J.29(5),1701-1710(2015)
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