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Rabusertib

Cat. No.：911222-45-2

  • CAS No. ：911222-45-2

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    • 产品名称: Rabusertib
      CAS No.: 911222-45-2
      Chemical Name:
      Synonyms:LY2603618; IC-83
      分子量:436.30
      分子式:C₁₈H₂₂BrN₅O₃
      SMILES:BrC(C=C1NC(NC2=NC=C(N=C2)C)=O)=C(C=C1OC[C@H]3OCCNC3)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • King, C., Diaz, H., Barnard, D., et al.Characterization and preclinical development of LY2603618: A selective and potent Chk1 inhibitorInvest New Drugs32(2),213-226(2014)', 'Wang, F.-Z., Fei, H.-r., Cui, Y.-J., et al.The checkpoint 1 kinase inhibitor LY2603618 induces cell cycle arrest, DNA damage response and autophagy in cancer cellsApoptosis19(9),1389-1398(2014)', 'Barnard, D., Diaz, H.B., Burke, T., et al.LY2603618, a selective CHK1 inhibitor, enhances the anti-tumor effect of gemcitabine in xenograft tumor modelsInvest New Drugs34(1),49-60(2016)
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