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Gemcitabine hydrochloride

Cat. No.：122111-03-9

  • CAS No. ：122111-03-9

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    • 产品名称: Gemcitabine hydrochloride
      CAS No.: 122111-03-9
      Chemical Name:
      Synonyms:盐酸吉西他滨; LY 188011 hydrochloride
      分子量:299.66
      分子式:C₉H₁₂ClF₂N₃O₄
      SMILES:OC[C@@H]1[C@H](C(F)(F)[C@H](N2C(N=C(C=C2)N)=O)O1)O.[H]Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Slusarczyk, M., Lopez, M.H., Balzarini, J., et al.Application of ProTide technology to gemcitabine: A successful approach to overcome the key cancer resistance mechanisms leads to a new agent (NUC-1031) in clinical developmentJ. Med. Chem.57(4),1531-1542(2014)', 'Bergman, A.M., Adema, A.D., Balzarini, J., et al.Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor modelsInvest. New Drugs29(3),456-466(2011)', "Veltkamp, S.A., Pluim, D., van Eijndhoven, M.A.J., et al.New insights into the pharmacology and cytotoxicity of gemcitabine and 2',2'-difluorodeoxyuridineMol. Cancer Ther.7(8),2415-2425(2008)", 'Merriman, R.L., Hertel, L.W., Schultz, R.M., et al.Comparison of the antitumor activity of gemcitabine and ara-C in a panel of human breast, colon, lung and pancreatic xenograft modelsInvest. New. Drugs14(3),243-247(1996)', 'Obradovic, A., Ager, C., Turunen, M., et al.Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulatorsCancer Cell41(5),933-949(2023)
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