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Tazobactam

Cat. No.:YN251315

  • CAS No. :89786-04-9

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    • 产品名称: Tazobactam
      CAS No.: 89786-04-9
      Chemical Name: (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 4,4-dioxide
      Synonyms:他唑巴坦; CL-298741; YTR-830H
      分子量:300.29
      分子式:C₁₀H₁₂N₄O₅S
      SMILES:O=C([C@@H]([C@@](CN1N=NC=C1)(C)S([C@]2([H])C3)(=O)=O)N2C3=O)O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Tazobactam是一种β-内酰胺酶抑制剂, 具有抗菌活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Drawz, S.M., and Bonomo, R.A.Three decades of β-lactamase inhibitorsClin. Microbiol. Rev.23(1),160-201(2010)

      Jones, R.N., Pfaller, M.A., Fuchs, P.C., et al.Piperacillin/tazobactam (YTR 830) combination. Comparative antimicrobial activity against 5889 recent aerobic clinical isolates and 60 Bacteroides fragilis group strainsDiagn. Microbiol. Infect. Dis.12(6),489-494(1989)

      Craig, W.A., and Andes, D.R.In vivo activities of ceftolozane, a new cephalosporin, with and without tazobactam against Pseudomonas aeruginosa and Enterobacteriaceae, including strains with extended-spectrum β-lactamases, in the thighs of neutropenic miceAntimicrob. Agents Chemother.57(4),1577-1582(2013)

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