Lumacaftor
Cat. No.：YN360414
CAS No. ：936727-05-8
| 产品名称: | Lumacaftor |
| CAS No.: | 936727-05-8 |
| Chemical Name: | 3-[6-[[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl]amino]-3-methyl-2-pyridinyl]-benzoic acid |
| Synonyms: | 鲁玛卡托; VX-809; VRT 826809 |
| 分子量: | 452.41 |
| 分子式: | C₂₄H₁₈F₂N₂O₅ |
| SMILES: | FC1(F)OC(C=C(C=C2)C3(CC3)C(NC4=NC(C5=CC=CC(C(O)=O)=C5)=C(C=C4)C)=O)=C2O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lumacaftor (VX-809; VRT 826809) 是CFTR调节剂，可纠正 CFTR 蛋白的折叠和运输。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Van Goor, F., Hadida, S., Grootenhuis, P.D., et al.Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809Proc. Natl. Acad. Sci. USA108(46),18843-18848(2011)
