Loxiglumide
Cat. No.：YN321694
CAS No. ：107097-80-3
| 产品名称: | Loxiglumide |
| CAS No.: | 107097-80-3 |
| Chemical Name: | 4-[(3,4-dichlorobenzoyl)amino]-5-[(3-methoxypropyl)pentylamino]-5-oxo-pentanoic acid |
| Synonyms: | CR-1505 |
| 分子量: | 461.38 |
| 分子式: | C₂₁H₃₀Cl₂N₂O₅ |
| SMILES: | O=C(O)CCC(NC(C1=CC=C(Cl)C(Cl)=C1)=O)C(N(CCCOC)CCCCC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Loxiglumide 是缩胆囊素 (CCK-1) 受体拮抗剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Setnikar, I., Bani, M., Cereda, R., et al.Pharmacological characterisation of a new potent and specific nonpolypeptidic cholecystokinin antagonistArzneimittelforschung37(6),703-707(1987)
Rakovska, A., Sgaragli, G., Mantovani, P., et al.Effect of loxiglumide (CR 1505) on CCK-induced contractions and 3H-acetylcholine release from guinea-pig gallbladderNeuropeptides25(5),271-276(1993)
Hirata, M., Itoh, M., Tsuchida, A., et al.Cholecystokinin receptor antagonist, loxiglumide, inhibits invasiveness of human pancreatic cancer cell linesFEBS. Lett.383(3),241-244(1996)
Nio, Y., Tsubono, M., Morimoto, H., et al.Loxiglumide (CR 1 505), a cholecystokinin antagonist, specifically inhibits the growth of human pancreatic cancer lines xenografted into nude miceCancer72(12),3599-3606(1993)
Tani, S., Itoh, H., Koide, M., et al.Involvement of endogenous cholecystokinin in the development of acute pancreatitis induced by closed duodenal loopPancreas8(1),109-115(1993)
