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> 产品中心 > 抑制剂 & 激动剂 > Epigenetics > DNA Methyltransferase

DC-05

Cat. No.:YN310184

  • CAS No. :890643-16-0

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    • 参考文献
    • 产品名称: DC-05
      CAS No.: 890643-16-0
      Chemical Name: α-[[[2-(1H-indol-3-yl)ethyl]amino]methyl]-9H-carbazole-9-ethanol
      Synonyms:DC-05
      分子量:383.49
      分子式:C₂₅H₂₅N₃O
      SMILES:OC(CNCCC1=CNC2=C1C=CC=C2)CN(C3=CC=CC=C34)C5=C4C=CC=C5
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: DC-05 是一种DNMT1抑制剂,IC50和Kd值分别为 10.3 μM 和 1.09 μM。
      IC50和靶点: [{name:"DNMT1:1.09 μM (Kd)"},{name: "DNMT1:10.3 μM (IC50)"},{name: "PRMT1:37.1 μM (IC50)"}]
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Chen, S., Wang, Y., Zhou, W., et al.Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screeningJ. Med. Chem.57(21),9028-9041(2014)

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