P005091
Cat. No.：YN290362
CAS No. ：882257-11-6
规格
价格(RMB)
库存
| 产品名称: | P005091 |
| CAS No.: | 882257-11-6 |
| Chemical Name: | 1-[5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl]-ethanone |
| Synonyms: | P5091 |
| 分子量: | 348.22 |
| 分子式: | C₁₂H₇Cl₂NO₃S₂ |
| SMILES: | CC(C1=CC([N+]([O-])=O)=C(SC2=CC=CC(Cl)=C2Cl)S1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | P005091 是一种有效的，选择性的泛素特异性蛋白酶7 (USP7) 抑制剂，EC50值为 4.2 μM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Chauhan, D., Tian, Z., Nicholson, B., et al.A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistanceCancer Cell22(3),345-358(2012)
Weinstock, J., Wu, J., Cao, P., et al.Selective dual inhibitors of the cancer-related deubiquitylating proteases USP7 and USP47ACS Med. Chem. Lett.3,789-792(2012)
