TCID
Cat. No.：YN290437
CAS No. ：30675-13-9
规格
价格(RMB)
库存
| 产品名称: | TCID |
| CAS No.: | 30675-13-9 |
| Chemical Name: | 4,5,6,7-tetrachloro-1H-indene-1,3(2H)-dione |
| Synonyms: | 4,5,6,7-Tetrachloroindan-1,3-dione |
| 分子量: | 283.92 |
| 分子式: | C₉H₂Cl₄O₂ |
| SMILES: | O=C1CC(C2=C1C(Cl)=C(Cl)C(Cl)=C2Cl)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TCID (4,5,6,7-Tetrachloroindan-1,3-dione) 是一种有效的选择性神经元泛素 C 末端水解酶 (UCH-L3) 抑制剂，IC50为 0.6 μM。TCID 减少脑干和脊髓原代神经元中的甘氨酸转运蛋白 GlyT2 泛素化。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
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Wada, H., Kito, K., Caskey, L.S., et al.Cleavage of the C-terminus of NEDD8 by UCH-L3Biochem. Biophys. Res. Commun.251(3),668-692(1998)
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Liu, Y., Lashuel, H.A., Choi, S., et al.Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell lineChem. Biol.10(9),837-846(2003)
