NIBR189
Cat. No.:YN320575
| 产品名称: | NIBR189 |
| CAS No.: | 1599432-08-2 |
| Chemical Name: | 3-(4-bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2E-propen-1-one |
| Synonyms: | NIBR-189; NIBR 189 |
| 分子量: | 429.31 |
| 分子式: | C₂₁H₂₁BrN₂O₃ |
| SMILES: | O=C(N1CCN(C(C2=CC=C(OC)C=C2)=O)CC1)/C=C/C3=CC=C(Br)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NIBR189是一个EBI2(GPR183)小分子拮抗剂,IC50值为11nM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Sun, S., and Liu, C.7α, 25-dihydroxycholesterol-mediated activation of EBI2 in immune regulation and diseasesFront. Pharmacol.6:60,(2015)
Gessier, F., Preuss, I., Yin, H., et al.Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptorJ. Med. Chem.57,3358-3368(2014)