NVP-BHG712
Cat. No.：YN440256
CAS No. ：940310-85-0
规格
价格(RMB)
库存
| 产品名称: | NVP-BHG712 |
| CAS No.: | 940310-85-0 |
| Chemical Name: | 4-methyl-3-[[1-methyl-6-(3-pyridinyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino]-N-[3-(trifluoromethyl)phenyl]-benzamide |
| Synonyms: | BHG712 |
| 分子量: | 503.48 |
| 分子式: | C₂₆H₂₀F₃N₇O |
| SMILES: | CC1=CC=C(C=C1NC2=NC(C3=CC=CN=C3)=NC4=C2C=NN4C)C(NC5=CC=CC(C(F)(F)F)=C5)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NVP-BHG712 是具有口服活性的EphB4 激酶自身磷酸化的抑制剂，其对EphA2 和EphB4 的IC50值分别为 3.3 nM 和 3 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Martiny-Baron, G., Holzer, P., Billy, E., et al.The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesisAngiogenesis13,259-267(2010)
