JI-101
Cat. No.：YN440360
CAS No. ：900573-88-8
规格
价格(RMB)
库存
| 产品名称: | JI-101 |
| CAS No.: | 900573-88-8 |
| Chemical Name: | N-[1-[(2-amino-4-pyridinyl)methyl]-1H-indol-4-yl]-N′-(5-bromo-2-methoxyphenyl)-urea |
| Synonyms: | JI 101,CGI-1842 |
| 分子量: | 466.33 |
| 分子式: | C₂₂H₂₀BrN₅O₂ |
| SMILES: | O=C(NC1=CC(Br)=CC=C1OC)NC2=CC=CC3=C2C=CN3CC4=CC(N)=NC=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JI-101是有口服活性的有抗癌活性的多靶点激酶抑制剂，可抑制VEGFR2，PDGFRβ和EphB4。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Velleca, M., Miller, L., Sharma, S., et al.Abstract 17: Preclinical and phase 1 trial results of JI-101, a novel, oral tyrosine kinase inhibitor that selectively targets VEGFR2, EphB4, and PDGFRβCancer Res.70(8 Suppl.),17(2010)
