CUDA
Cat. No.：YN370925
CAS No. ：479413-68-8
| 产品名称: | CUDA |
| CAS No.: | 479413-68-8 |
| Chemical Name: | 12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid |
| Synonyms: | |
| 分子量: | 340.50 |
| 分子式: | C₁₉H₃₆N₂O₃ |
| SMILES: | O=C(NC1CCCCC1)NCCCCCCCCCCCC(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CUDA 是一种有效的可溶性环氧水解酶 (sEH) 抑制剂，对小鼠 sEH 和人 sEH 作用的IC50分别为 11.1 nM 和 112 nM。CUDA 能选择性地上调过氧化物酶体增殖激活受体PPARalpha的活性。CUDA 可能对心血管疾病的研究有价值。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
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Morisseau, C., Goodrow, M.H., Newman, J.W., et al.Structural refinement of inhibitors of urea-based soluble epoxide hydrolasesBiochem. Pharmacol.63(9),1599-1608(2002)
Fang, X., Hu, S., Watanabe, T., et al.Activation of peroxisome proliferator-activated receptor α by substituted urea-derived soluble epoxide hydrolase inhibitorsJ. Pharmacol. Exp. Ther.314(1),260-270(2005)
