Pioglitazone

Cat. No.：111025-46-8

CAS No. ：111025-46-8

产品名称:	Pioglitazone
CAS No.:	111025-46-8
Chemical Name:
Synonyms:	吡格列酮; U 72107
分子量:	356.44
分子式:	C₁₉H₂₀N₂O₃S
SMILES:	O=C(N1)SC(CC2=CC=C(OCCC3=NC=C(CC)C=C3)C=C2)C1=O
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 0.98

Sakamoto, J., Kimura, H., Moriyama, S., et al.Activation of human peroxisome proliferator-activated receptor (PPAR) subtypes by pioglitazoneBiochem. Biophys. Res. Commun.278(3),704-711(2000)', 'Willson, T.M., Brown, P.J., Sternbach, D.D., et al.The PPARs: From orphan receptors to drug discoveryJ. Med. Chem.43(4),527-550(2000)', 'Shannon, C.E., Daniele, G., Galindo, C., et al.Pioglitazone inhibits mitochondrial pyruvate metabolism and glucose production in hepatocytesFEBS J.284(3),451-465(2017)', 'Sugiyama, Y., Taketomi, S., Shimura, Y., et al.Effects of pioglitazone on glucose and lipid metabolism in Wistar fatty ratsArzneimittelforschung.40(3),263-267(1990)', 'Suzuki, S., Mori, Y., Nagano, A., et al.Pioglitazone, a peroxisome proliferator-activated receptor γ agonist, suppresses rat prostate carcinogenesisInt. J. Mol. Sci.17(12),pii: E2071(2016)', 'Zhao, Q., Wu, X., Yan, S., et al.The antidepressant-like effects of pioglitazone in a chronic mild stress mouse model are associated with PPARγ-mediated alteration of microglial activation phenotypesJ. Neuroinflammation13(1),259(2016)