Pifithrin-β hydrobromide

Cat. No.：511296-88-1

CAS No. ：511296-88-1

产品名称:	Pifithrin-β hydrobromide
CAS No.:	511296-88-1
Chemical Name:
Synonyms:	PFT β hydrobromide
分子量:	349.29
分子式:	C₁₆H₁₇BrN₂S
SMILES:	CC1=CC=C(C2=CN3C(SC4=C3CCCC4)=N2)C=C1.Br
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

Select Batch:

Purity: 0.98

Komarov, P.G., Komarova, E.A., Kondratov, R.V., et al.A chemical inhibitor of p53 that protects mice from the side effects of cancer therapyScience285(5434),1733-1737(1999)', 'Walton, M.I., Wilson, S.C., Hardcastle, I.R., et al.An evaluation of the ability of pifithrin-α and -β to inhibit p53 function in two wild-type p53 human tumor cell linesMol. Cancer Ther.4(9),1369-1377(2005)', 'Christodoulou, M.S., Colombo, F., Passarella, D., et al.Synthesis and biological evaluation of imidazolo[2,1-b]benzothiazole derivatives, as potential p53 inhibitorsBioorg. Med. Chem.19(5),1649-1657(2011)', 'Tasdemir, E., Maiuri, M.C., Orhon, I., et al.p53 represses autophagy in a cell cycle-dependent fashionCell Cycle7(19),3006-3011(2008)', 'Zuco, V., and Zunino, F.Cyclic pifithrin-α sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosisNeoplasia10(6),587-596(2008)', 'Kadekaro, A.L., Chen, J., Yang, J., et al.Alpha-melanocyte-stimulating hormone suppresses oxidative stress through a p53-mediated signaling pathway in human melanocytesMol. Cancer Res.10(6),778-786(2012)