Griseofulvin
Cat. No.：YN250759
| 产品名称: | Griseofulvin |
| CAS No.: | 126-07-8 |
| Chemical Name: | 7-chloro-2',4,6-trimethoxy-6'R-methyl-spiro[benzofuran-2(3H)-1'S-[2]cyclohexene]-3,4'-dione |
| Synonyms: | 灰黄霉素 |
| 分子量: | 352.77 |
| 分子式: | C₁₇H₁₇ClO₆ |
| SMILES: | O=C1[C@]2(C(OC)=CC(C[C@H]2C)=O)OC3=C(Cl)C(OC)=CC(OC)=C13 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Griseofulvin(Gris-PEG; Grifulvin)是一抗真菌感染试剂。 |
| IC50和靶点: | |
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Cacho, R.A., Chooi, Y.-H., Zhou, H., et al.Complexity generation in fungal polyketide biosynthesis: A spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvinACS Chem. Biol.8(10),2322-2330(2013)
Flint, A., Forsey, R.R., and Usher, B.Griseofulvin, a new oral antibiotic for the treatment of fungous infections of the skinCan. Med. Assoc. J.81(3),173-175(1959)
Roobol, A., Gull, K., and Pogson, C.I.Inhibition by griseofulvin of microtubule assembly in vitroFEBS Lett.67(3),248-251(1976)
Roth, F.J., Jr., Sallman, B., and Blank, H.In vitro studies of the antifungal antibiotic griseofulvinJ. Invest. Dermatol.33,403-418(1959)
Gentles, J.C.Experimental ringworm in guinea pigs: Oral treatment with griseofulvinNature182(4633),476-477(1958)
Ho, Y.-S., Duh, J.-S., Jeng, J.-H., et al.Griseofulvin potentiates antitumorigenesis effects of nocodazole through induction of apoptosis and G2/M cell cycle arrest in human colorectal cancer cellsInt. J. Cancer91(3),393-401(2001)
