Filipin III
Cat. No.：YN251699
| 产品名称: | Filipin III |
| CAS No.: | 480-49-9 |
| Chemical Name: | 4S,6S,8S,10R,12R,14R,16S,27S-octahydroxy-3R-(1R-hydroxy-hexyl)17,28R-dimethyl-oxacyclooctacosa-17E,19E,21E,21E,23E,25E-pentaen-2-one |
| Synonyms: | 菲律宾菌素 III |
| 分子量: | 654.83 |
| 分子式: | C₃₅H₅₈O₁₁ |
| SMILES: | O=C1O[C@H](C)[C@@H](O)/C=C/C=C/C=C/C=C/C=C(C)/[C@@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)[C@H]1[C@H](O)CCCCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Filipin III 是 Filipin 的主要成分，Filipin 是一种 28-元环五烯大环内酯类抗真菌抗生素，由S. filipinensis，S. avermitilis和S. miharaensis产生。Filipin 可以与膜甾醇相互作用导致膜结构的改变。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Castanho, M.A., Coutinho, A., and Prieto, M.J.Absorption and fluorescence spectra of polyene antibiotics in the presence of cholesterolJ. Biol. Chem.267(1),204-209(1992)
Miller, R.G.Mini Review. The use and abuse of filipin to localize cholesterol in membranesCell Biol. Int. Rep.8(7),519-535(1984)
Severs, N.J., and Robenek, H.Detection of microdomains in biomembranes. An appraisal of recent developments in freeze-fracture cytochemistryBiochim. Biophys. Acta737,373-408(1983)
