Oligomycin C
Cat. No.:YN251713
产品名称: | Oligomycin C |
CAS No.: | 11052-72-5 |
Chemical Name: | (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11S,12S,14S,15S,16R,18E,20E,22R,25S,28S,29R)-22-ethyl-3',4',5',6'-tetrahydro-7,11,15-trihydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H] |
Synonyms: | 寡霉素C |
分子量: | 775.06 |
分子式: | C₄₅H₇₄O₁₀ |
SMILES: | O=C([C@@H]([C@H]([C@@H](C([C@H]([C@H]([C@@H](C/C=C/C=C/[C@@]([H])(CC[C@]1([C@H]([C@@]([H])(O2)[C@@H]([C@]3(O1)CC[C@@H]([C@@]([H])(O3)C[C@@H](C)O)C)C)C)[H])CC)C)O)C)=O)C)O)C)[C@H]([C@@H]([C@H](/C=C/C2=O)C)O)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Oligomycin C 是由链霉菌产生的大环内酯类抗生素。Oligomycin C 对Aspergillus niger,Alternaria alternata,Botrytis cinerea,Phytophthora capsici表现出较强的抗黑曲霉活性,但对细菌没有活性。 |
IC50和靶点: | |
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Hong, S., and Pedersen, P.L.ATP synthase and the actions of inhibitors utilized to study its roles in human health, disease, and other scientific areasMicrobiol. Mol. Biol. Rev.72(4),590-641(2008)
Marton, A., Mihalik, R., Bratincsak, A., et al.Apoptotic cell death induced by inhibitors of energy conservation--Bcl-2 inhibits apoptosis downstream of a fall of ATP levelEur. J. Biochem.250(2),467-475(1997)