Climbazole
Cat. No.：YN251241
CAS No. ：38083-17-9
| 产品名称: | Climbazole |
| CAS No.: | 38083-17-9 |
| Chemical Name: | 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl-2-butanone |
| Synonyms: | 甘宝素; BAY-e 6975 |
| 分子量: | 292.76 |
| 分子式: | C₁₅H₁₇ClN₂O₂ |
| SMILES: | CC(C)(C)C(C(OC1=CC=C(Cl)C=C1)N2C=CN=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Climbazole (BAY-e 6975) 是一种有效的抗真菌剂 (antifungal)。具有抗头皮屑效果。Climbazole 还是大鼠肝细胞色素 P450 的强诱导剂。 |
| IC50和靶点: | |
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Cavana, P., Petit, J.Y., Perrot, S., et al.Efficacy of a 2% climbazole shampoo for reducing Malassezia population sizes on the skin of naturally infected dogsJ. Mycol. Med.25(4),268-273(2015)
Stylianou, M., Kulesskiy, E., Lopes, J.P., et al.Antifungal application of nonantifungal drugsAntimicrob. Agents Chemother.58(2),1055-1062(2014)
Schmidt, A.In vitro activity of climbazole, clotrimazole and silver-sulphadiazine against isolates of Malassezia pachydermatisZentralbl. Veterinarmed. B44(4),193-197(1997)
Schmidt, A., and Rühl-Hörster, B.In vitro susceptibility of Malassezia furfur against azole compoundsMycoses39(7-8),309-312(1996)
Kobayashi, Y., Suzuki, M., Ohshiro, N., et al.Climbazole is a new potent inducer of rat hepatic cytochrome P450J. Toxicol. Sci.26(3),141-150(2001)
