BSJ-03-204
Cat. No.：YN430223
CAS No. ：2349356-09-6
规格
价格(RMB)
库存
| 产品名称: | BSJ-03-204 |
| CAS No.: | 2349356-09-6 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 832.90 |
| 分子式: | C₄₃H₄₈N₁₀O₈ |
| SMILES: | O=C1N(C2CCCC2)C3=NC(NC4=CC=C(N(CC5)CCN5CCCCNC(COC6=C(C(N7C(CCC8=O)C(N8)=O)=O)C(C7=O)=CC=C6)=O)C=N4)=NC=C3C(C)=C1C(C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BSJ-03-204 是一种有效的，选择性的基于 Palbociclib (HY-50767) 的CDK4/6双重降解剂 (PROTAC)，对 CDK4/D1 和 CDK6/D1 的IC50分别为 26.9 nM 和 10.4 nM。BSJ-03-204 不诱导 IKZF1/3 降解，具有抗癌活性。 |
| IC50和靶点: | [{name:"CDK4/D1:26.9 nM (IC50)"},{name: "CDK6/D1:10.4 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
