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STF-31

Cat. No.:YN360661

  • CAS No. :724741-75-7

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    • 参考文献
    • 产品名称: STF-31
      CAS No.: 724741-75-7
      Chemical Name: 4-[[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinyl-benzamide
      Synonyms:STF31,STF 31
      分子量:423.53
      分子式:C₂₃H₂₅N₃O₃S
      SMILES:O=C(NC1=CC=CN=C1)C2=CC=C(CNS(=O)(C3=CC=C(C(C)(C)C)C=C3)=O)C=C2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: STF-31 是一种葡萄糖转运蛋白 1(GLUT1) 的选择性抑制剂,IC50为 1 μM。
      IC50和靶点: [{name:"GLUT1:1 μM (IC50)"}]
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Chan, D.A., Sutphin, P.D., Nguyen, P., et al.Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethalitySci. Transl. Med.3(94),1-9(2011)

      Adams, D.J., Ito, D., Rees, M.G., et al.NAMPT is the cellular target of STF-31-like small-molecule probesACS Chem. Biol.9(10),2247-2254(2014)

      Garten, A., Petzold, S., Körner, A., et al.Nampt: Linking NAD biology, metabolism, and cancerTrends Endocrinol. Metab.20(3),130-138(2009)

      Boheler, K.R., Bhattacharya, S., Kropp, E.M., et al.A human pluripotent stem cell surface N-glycoproteome resource reveals markers, extracellular epitopes, and drug targetsStem Cell Reports3,185-203(2014)

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