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Loteprednol Etabonate

Cat. No.:YN321119

  • CAS No. :82034-46-6

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    • 参考文献
    • 产品名称: Loteprednol Etabonate
      CAS No.: 82034-46-6
      Chemical Name: (11β,17α)-17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-androsta-1,4-diene-17-carboxylic acid, chloromethyl ester
      Synonyms:Alrex,氯替泼诺,Lotemax
      分子量:466.95
      分子式:C₂₄H₃₁ClO₇
      SMILES:O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(OC(OCC)=O)C(OCCl)=O)=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Loteprednol etabonate (LE) 是口服有效的“软”类固醇,是一种糖皮质激素。Loteprednol etabonate (LE) 具有抗炎活性,可用于验光等眼科研究。
      IC50和靶点:
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    • Druzgala, P., Hochhaus, G., and Bodor, N.Soft drugs--10. Blanching activity and receptor binding affinity of a new type of glucocorticoid: loteprednol etabonateJ. Steroid Biochem. Mol. Biol.38(2),149-154(1991)

      Bodor, N.S., Kiss-Buris, S.T., and Buris, L.Novel soft steroids: Effects on cell growth in vitro and on wound healing in the mouseSteroids56(8),434-439(1991)

      Bodor, N., and Varga, M.Effect of a novel soft steroid on the wound healing of rabbit corneaExp. Eye Res.50(2),183-187(1990)

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