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Medroxyprogesterone acetate

Cat. No.:YN321511

  • CAS No. :71-58-9

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    • 参考文献
    • 产品名称: Medroxyprogesterone acetate
      CAS No.: 71-58-9
      Chemical Name: 17-(acetyloxy)-6α-methyl-pregn-4-ene-3,20-dione
      Synonyms:醋酸甲羟孕酮; Medroxyprogesterone 17-acetate; MPA
      分子量:386.52
      分子式:C₂₄H₃₄O₄
      SMILES:CC(O[C@@]([C@]12C)(CC[C@@]1([H])[C@@](C[C@H](C)C3=CC4=O)([H])[C@]([C@]3(CC4)C)([H])CC2)C(C)=O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Medroxyprogesterone acetate 是一种广泛使用的合成类固醇,与孕酮 (progesterone),雄激素 (androgen) 和糖皮质激素受体 (glucocorticoid receptors) 都有作用。
      IC50和靶点:
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      In Vivo:
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    • Chang, M.C.Effects of medroxyprogesterone acetate and of ethinyl oestradiol on the fertilization and transportation of ferret eggsJ. Reprod. Fertil.13(1),173-174(1967)

      Dickmann, Z.Short- and long-term effects of a single injection of depo-medroxyprogesterone acetate (provera) on the vaginal smear, ovulation and mating in the ratJ. Reprod. Fertil.32(3),447-451(1973)

      Albin, J., Vittek, J., Gordon, G.G., et al.On the mechanism of the anti-androgenic effect of medroxyprogesterone acetateEndocrinology93(2),(1973)

      Huijbregts, R.P., Michel, K.G., and Hel, Z.Effect of progestins on immunity: Medroxyprogesterone but not norethisterone or levonorgestrel suppresses the function of T cells and pDCsContraception90(2),123-129(2014)

      Turcotte, J.G., Haines, R.F., Brody, G.L., et al.Immunosuppression with medroxyprogesterone acetateTransplantation6(2),248-260(1968)

      Hofmeyr, G.J., Singata-Madliki, M., Lawrie, T.A., et al.Effects of the copper intrauterine device versus injectable progestin contraception on pregnancy rates and method discontinuation among women attending termination of pregnancy services in South Africa: A pragmatic randomized controlled trialReprod. Health13,42(2016)

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