Triamcinolone
Cat. No.：YN321454
CAS No. ：124-94-7
| 产品名称: | Triamcinolone |
| CAS No.: | 124-94-7 |
| Chemical Name: | (11β,16α)-9-fluoro-11,16,17,21-tetrahydroxy-pregna-1,4-diene-3,20-dione |
| Synonyms: | 曲安奈德 |
| 分子量: | 394.43 |
| 分子式: | C₂₁H₂₇FO₆ |
| SMILES: | F[C@@]1([C@]2(C=C3)C)[C@](CCC2=CC3=O)([H])[C@@](C[C@@H](O)[C@]4(O)C(CO)=O)([H])[C@]4(C)C[C@@H]1O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Triamcinolone 是合成的长效糖皮质激素，是皮质类固醇激素受体 (corticosteroid hormone receptor) 激动剂，具有抗炎作用。 |
| IC50和靶点: | |
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Hayashi, R., Xiao, W., Kawamoto, M., et al.Systemic glucocorticoid therapy reduces pain and the number of endoneurial tumor necrosis factor-alpha (TNFα)-positive mast cells in rats with a painful peripheral neuropathyJ. Pharmacol. Sci.106(4),599-565(2008)
Uete, T., and Ashmore, J.Effects of triamcinolone on carbohydrate synthesis by rat liver slicesJ. Biol. Chem.238(9),2906-2911(1963)
Wada, S., Udagawa, N., Akatsu, T., et al.Regulation by calcitonin and glucocorticoids of calcitonin receptor gene expression in mouse osteoclastsEndocrinology138(2),521-529(1997)
Shetlar, M.R., Shetlar, D.J., Bloom, R.F., et al.Involution of keloid implants in athymic mice treated with pirfenidone or with triamcinoloneJ. Lab Clin. Med.132(6),491-496(1998)
