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Cortisone acetate

Cat. No.:YN321143

  • CAS No. :50-04-4

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    • 参考文献
    • 产品名称: Cortisone acetate
      CAS No.: 50-04-4
      Chemical Name: 21-(acetyloxy)-17-hydroxy-pregn-4-ene-3,11,20-trione
      Synonyms:醋酸可的松; Cortisone 21-acetate
      分子量:402.48
      分子式:C₂₃H₃₀O₆
      SMILES:C[C@@]1(C2)[C@](C(COC(C)=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])C2=O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Cortisone acetate (Cortisone 21-acetate),是 Cortisol(一种糖皮质激素)的氧化代谢产物。Cortisone acetate 具有免疫抑制和消炎的作用。Cortisone acetate 在高浓度下可以部分干预 Glucocorticoid 与Glucocorticoid-receptor的结合。
      IC50和靶点:
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      In Vivo:
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      Solvent & Solubility:
    • McCue, R.E., Dannenberg, A.M., Jr., Huguchi, S., et al.The effect of cortisone on the accumulation, activation, and necrosis of macrophages in tuberculous lesionsInflammation3(2),159-176(1978)

      Joseph, J., and Tydd, M.The effects of cortisone acetate on tissue regeneration in the rabbit's earJ. Anat.115(Pt. 3),445-460(1973)

      Schlechte, J.A., Ginsberg, B.H., and Sherman, B.M.Regulation of the glucocorticoid receptor in human lymphocytesJ. Steroid Biochem.16(1),69-74(1982)

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