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Bicyclol

Cat. No.:YN251128

  • CAS No. :118159-48-1

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    • 生物活性
    • 参考文献
    • 产品名称: Bicyclol
      CAS No.: 118159-48-1
      Chemical Name: 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bi-1,3-benzodioxole]-5-carboxylic acid, methyl ester
      Synonyms:双环醇; SY801
      分子量:390.34
      分子式:C₁₉H₁₈O₉
      SMILES:O=C(C1=CC(OC)=C(OCO2)C2=C1C3=C4OCOC4=C(OC)C=C3CO)OC
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Bicyclol(SY 801)是可口服的抗HBV,HCV化合物。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Liu, G.T.Bicyclol: A novel drug for treating chronic viral hepatitis B and CMed. Chem.5(1),29-43(2009)

      Li, M., and Liu, G.T.Inhibition of Fas/FasL mRNA expression and TNF-a release in concanavalin A-induced liver injury in mice by bicyclolWorld J. Gastroenterol.10(12),1775-1790(2004)

      Yu, L., Wei, H., and Liu, G.A novel antihepatitis drug, bicyclol, prevents liver carcinogenesis in diethylnitrosamine-initiated and phenobarbital-promoted mice tumor modelJ. Biomed. Biotechnol.,(2012)

      Zhen, Y.Z., Li, N.R., He, H.W., et al.Protective effect of bicyclol against bile duct ligation-induced hepatic fibrosis in ratsWorld J. Gastroenterol.21(23),7155-7164(2015)

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