PSI-6130
Cat. No.：YN250064
CAS No. ：817204-33-4
| 产品名称: | PSI-6130 |
| CAS No.: | 817204-33-4 |
| Chemical Name: | (2'R)-2'-deoxy-2'-fluoro-2'-methyl-cytidine |
| Synonyms: | R 1656 |
| 分子量: | 259.23 |
| 分子式: | C₁₀H₁₄FN₃O₄ |
| SMILES: | O=C1N=C(C=CN1[C@@H]([C@@](C)([C@@H]2O)F)O[C@@H]2CO)N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PSI-6130 是高效的，有选择性的HCV NS5B polymerase抑制剂，能够抑制HCV复制，IC50值为 0.6 μM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Murakami, E., Bao, H., Ramesh, M., et al.Mechanism of activation of β-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymeraseAntimicrob. Agents Chemother.51(2),503-509(2007)
Stuyver, L.J., McBrayer, T.R., Tharnish, P.M., et al.Inhibition of hepatitis C replicon RNA synthesis by β-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine: A specific inhibitor of hepatitis C virus replicationAntivir. Chem. Chemother.17(2),79-87(2006)
