Ombitasvir
Cat. No.：YN250578
CAS No. ：1258226-87-7
| 产品名称: | Ombitasvir |
| CAS No.: | 1258226-87-7 |
| Chemical Name: | 2,2'-[[(2S,5S)-1-[4-(1,1-dimethylethyl)phenyl]-2,5-pyrrolidinediyl]di-4,1-phenylene]bis[N-(methoxycarbonyl)-L-valyl-L-prolinamide |
| Synonyms: | 奥比他韦; ABT-267 |
| 分子量: | 894.11 |
| 分子式: | C₅₀H₆₇N₇O₈ |
| SMILES: | CC(C)(C)C(C=C1)=CC=C1N2[C@H](C3=CC=C(NC([C@H]4N(C([C@@H](NC(OC)=O)C(C)C)=O)CCC4)=O)C=C3)CC[C@H]2C5=CC=C(NC([C@@H]6CCCN6C([C@@H](NC(OC)=O)C(C)C)=O)=O)C=C5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ombitasvir 是一种HCV NS5A抑制剂，对 HCV 基因型 1-5 和 6a 的EC50值分别为 0.82-19.3 pM 和 366 pM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Zhang, X.Direct anti-HCV agentsActa Pharmaceutica Sinica B6(1),26-31(2015)
Krishnan, P., Beyer, J., Mistry, N., et al.In vitro and in vivo antiviral activity and resistance profile of ombitasvir, an inhibitor of hepatitis C virus NS5AAntimicrob. Agents Chemother.59(2),979-987(2015)
