NM107
Cat. No.：YN250109
CAS No. ：20724-73-6
| 产品名称: | NM107 |
| CAS No.: | 20724-73-6 |
| Chemical Name: | 2'-C-methyl-cytidine |
| Synonyms: | 2'-C-Methylcytidine; NM-107 |
| 分子量: | 257.24 |
| 分子式: | C₁₀H₁₅N₃O₅ |
| SMILES: | NC(C=CN1[C@@H]2O[C@H](CO)[C@@H](O)[C@@]2(C)O)=NC1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NM107 (2'-C-Methylcytidine) 是丙型肝炎病毒 (HCV) NS5B 聚合酶的核苷抑制剂，其在野生型复制子细胞中的EC50为 1.85 μM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Benzaria, S., Bardiot, D., Bouisset, T., et al.2′-C-Methyl branched pyrimidine ribonucleoside analogues: Potent inhibitors of RNA virus replicationAntivir. Chem. Chemother.18(4),225-242(2007)
Goris, N., De Palma, A., Toussaint, J.F., et al.2'-C-methylcytidine as a potent and selective inhibitor of the replication of foot-and-mouth disease virusAntiviral Res.73(3),161-168(2007)
Rocha-Pereira, J., Van Dycke, J., and Neyts, J.Treatment with a nucleoside polymerase inhibitor reduces shedding of murine norovirus in stool to undetectable levels without emergence of drug-resistant variantsAntimicrob. Agents Chemother.60(3),1907-1911(2015)
