SW-100
Cat. No.：YN290149
CAS No. ：2126744-35-0
| 产品名称: | SW-100 |
| CAS No.: | 2126744-35-0 |
| Chemical Name: | |
| Synonyms: | 4-[(6-Chloro-3,4-dihydro-2H-quinolin-1-yl)methyl]-N-hydroxybenzamide |
| 分子量: | 316.78 |
| 分子式: | C₁₇H₁₇ClN₂O₂ |
| SMILES: | O=C(NO)C1=CC=C(CN2CCCC3=C2C=CC(Cl)=C3)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SW-100 是一种有效的组蛋白脱乙酰基酶 6(HDAC6)抑制剂，IC50值为 2.3 nM，相对于其他 HDAC 酶，对 HDAC6 的选择性至少高 1000倍。SW-100 显著提高了跨越血脑屏障的能力。 |
| IC50和靶点: | [{name:"HDAC1:5.23 μM (IC50)"},{name: "HDAC2:32.8 μM (IC50)"},{name: "HDAC3:29.5 μM (IC50)"},{name: "HDAC4:10.9 μM (IC50)"},{name: "HDAC5:4.07 μM (IC50)"},{name: "HDAC6:2.3 nM (IC50)"},{name: "HDAC7:4.55 μM (IC50)"},{name: "HDAC8:3.72 μM (IC50)"},{name: "HDAC9:3.46 μM (IC50)"},{name: "HDAC10:26.2 μM (IC50)"},{name: "HDAC11:5.72 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
