Tenofovir alafenamide
Cat. No.：YN250621
CAS No. ：379270-37-8
| 产品名称: | Tenofovir alafenamide |
| CAS No.: | 379270-37-8 |
| Chemical Name: | N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-L-alanine, 1-methylethyl ester |
| Synonyms: | 替诺福韦艾拉酚胺; GS-7340 |
| 分子量: | 476.47 |
| 分子式: | C₂₁H₂₉N₆O₅P |
| SMILES: | NC1=NC=NC2=C1N=CN2C[C@@H](C)OC[P@](OC3=CC=CC=C3)(N[C@@H](C)C(OC(C)C)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tenofovir alafenamide (GS-7340) 是 Tenofovir 的前体，Tenofovir 是一种HIV-1核苷酸逆转录酶抑制剂。 |
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Lee, W.A., He, G.X., Eisenberg, E., et al.Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissueAntimicrob. Agents Chemother.49(5),1898-1906(2005)
