HA15
Cat. No.：YN370048
CAS No. ：1609402-14-3
| 产品名称: | HA15 |
| CAS No.: | 1609402-14-3 |
| Chemical Name: | N-[4-[3-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]phenyl]-2-thiazolyl]-acetamide |
| Synonyms: | HA15;HA-15;N-[4-[3-[[[5-(Dimethylamino)-1-naphthalenyl]sulfonyl]amino]phenyl]-2-thiazolyl]-acetamide;N-(4-(3-((5-(dimethylamino)naphthalene)-1-sulfonamido)phenyl)thiazol-2-yl)acetamide;HA15 pound>>HA 15;BCP28914;NSC782989;s8299;HA15, >=98% (HPLC);AK685666 |
| 分子量: | 466.58 |
| 分子式: | C₂₃H₂₂N₄O₃S₂ |
| SMILES: | CC(NC1=NC(C2=CC=CC(NS(=O)(C3=C4C=CC=C(N(C)C)C4=CC=C3)=O)=C2)=CS1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | HA15 是一种高效特异性的内质网伴侣蛋白BiP/GRP78/HSPA5抑制剂，可抑制 BiP 的 ATP 酶活性，具有抗肿瘤活性。 |
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Cerezo, M., Lehraiki, A., Millet, A., et al.Compounds triggering ER stress exert anti-melanoma effects and overcome BRAF inhibitor resistanceCancer Cell29(6),805-819(2016)
Han, C., Xie, K., Yang, C., et al.HA15 alleviates bone loss in ovariectomy-induced osteoporosis by targeting HSPA5Exp. Cell Res.406(2),112781(2021)
