SANT-1
Cat. No.：YN450003
CAS No. ：304909-07-7
规格
价格(RMB)
库存
| 产品名称: | SANT-1 |
| CAS No.: | 304909-07-7 |
| Chemical Name: | N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine |
| Synonyms: | SANT 1 |
| 分子量: | 373.49 |
| 分子式: | C₂₃H₂₇N₅ |
| SMILES: | CC1=C(/C=N/N2CCN(CC3=CC=CC=C3)CC2)C(C)=NN1C4=CC=CC=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SANT-1 是一种有效的Smo拮抗剂，能够抑制Hedgehog通路，在 Shh-LIGHT2 和 SmoA1-LIGHT2 实验中，IC50值分别为 20 nM 和 30 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
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Rominger, C.M., Bee, W.L.T., Copeland, R.A., et al.Evidence for allosteric interactions of antagonist binding to the smoothened receptorJ. Pharmacol. Exp. Ther.329(3),995-1005(2009)
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