Ciliobrevin D
Cat. No.：YN450053
CAS No. ：1370554-01-0
规格
价格(RMB)
库存
| 产品名称: | Ciliobrevin D |
| CAS No.: | 1370554-01-0 |
| Chemical Name: | 2,4-Dichloro-α-(7-chloro-3,4-dihydro-4-oxo-2(1H)-quinazolinylidene)-β-oxo-benzenepropanenitrile |
| Synonyms: | |
| 分子量: | 392.62 |
| 分子式: | C₁₇H₈Cl₃N₃O₂ |
| SMILES: | O=C(C1=C(C=C(Cl)C=C1)Cl)/C(C#N)=C(N2)/NC3=CC(Cl)=CC=C3C2=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ciliobrevin D 是一种细胞渗透性，可逆和特异性的 AAA + ATPase 运动细胞质动力蛋白抑制剂。Ciliobrevin D 抑制Hedgehog (Hh)信号和初级纤毛形成。Ciliobrevin D 在体外抑制依赖于动力蛋白的微管滑动和 ATPase 活性。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Firestone, A., et al.: Nature, 484, 125 (2012)
