NBI-98782
Cat. No.：YN360565
CAS No. ：85081-18-1
| 产品名称: | NBI-98782 |
| CAS No.: | 85081-18-1 |
| Chemical Name: | (2R,3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; [2R-(2α,3β,11bβ)]-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; (+)-(2R,3R,11bR)-Dihydrotetrabenazine; (+)-DTBZ; (+) |
| Synonyms: | (+)-α-二氢丁苯那嗪; (+)-DTBZ; (+)-α-Dihydrotetrabenazine; (+)-α-DHTBZ |
| 分子量: | 319.44 |
| 分子式: | C₁₉H₂₉NO₃ |
| SMILES: | COC(C=C1CCN2C[C@@H](CC(C)C)[C@@H]3O)=C(C=C1[C@]2(C3)[H])OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NBI-98782(alpha-dihydrotetrabenazine)是囊泡单胺转运体（VMAT2）抑制剂，Ki为0.97nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Yao, Z., et al.: Eur. J. Med. Chem., 46, 1841 (2011)
Rishel, M.J., et al.: J. Org. Chem., 74, 4001 (2009)
