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α-Cyano-4-hydroxycinnamic acid

Cat. No.:YN360189

  • CAS No. :28166-41-8

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    • 参考文献
    • 产品名称: α-Cyano-4-hydroxycinnamic acid
      CAS No.: 28166-41-8
      Chemical Name: 2-cyano-3-(4-hydroxyphenyl)-2-propenoic acid
      Synonyms:α-Cyano-4-hydroxycinnamate
      分子量:189.17
      分子式:C₁₀H₇NO₃
      SMILES:O=C(O)/C(C#N)=C/C1=CC=C(O)C=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) 是有效的非竞争性单羧酸盐转运蛋白 (MCTs) 抑制剂。α-Cyano-4-hydroxycinnamic acid 抑制线粒体丙酮酸转运蛋白,Ki值为 6.3 μM。α-Cyano-4-hydroxycinnamic acid 用作基质辅助激光解吸电离-飞行时间质谱 (MALDI-TOF) 分析的基质,可以促进肽离子化。
      IC50和靶点:
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    • Halestrap, A.P.The mitochondrial pyruvate carrier: Kinetics and specificity for substrates and inhibitorsBiochem. J.148(1),85-96(1975)

      Watanabe, M., Terasawa, K., Kaneshiro, K., et al.Improvement of mass spectrometry analysis of glycoproteins by MALDI-MS using 3-aminoquinoline/α-cyano-4-hydroxycinnamic acidAnal. Bioanal. Chem.405(12),4289-4293(2013)

      Yang, H., Wan, D., Song, F., et al.α-Cyano-4-hydroxycinnamic acid, sinapinic acid, and ferulic acid as matrices and alkylating agents for matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of cysteine-containing peptidesRapid Commun. Mass Spectrom.27(12),1410-1412(2013)

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