Citreoviridin
Cat. No.：YN361001
| 产品名称: | Citreoviridin |
| CAS No.: | 25425-12-1 |
| Chemical Name: | 2,5-anhydro-1,6-dideoxy-2-C-[(8-(4-methoxy-5-methyl-2-oxo-2H-pyran-6-yl)-2-methyl-1E,3E,5E,7E-octatetraen-1-yl]-4-C-methyl-D-iditol |
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| 分子量: | 402.48 |
| 分子式: | C₂₃H₃₀O₆ |
| SMILES: | CC(/C=C/C=C/C=C/C(O1)=C(C(OC)=CC1=O)C)=C\[C@]2([C@H](O)[C@]([C@H](O2)C)(O)C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Citreoviridin 是一种来自Penicillium citreovirideNRRL 2579 的毒素，抑制脑突触体Na+/K+ATPase，而在微粒体中，刺激Na+/K+-ATPase和 Mg2+-ATPase 活性。Citreoviridin 作用于人脐静脉内皮细胞，抑制细胞增殖并促进凋亡 (apoptosis)。 |
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Linnett, P.E., Mitchell, A.D., Osselton, M.D., et al.Citreoviridin, a specific inhibitor of the mitochondiral adenosine triphosphataseBiochem. J.170(3),503-510(1978)
Gause, E.M., Buck, M.A., and Douglas, M.G.Binding of citreoviridin to the β subunit of the yeast F1-ATPaseJ. Biol. Chem.256(2),557-559(1981)
Wu, Y.H., Hu, C.W., Chien, C.W., et al.Quantitative proteomic analysis of human lung tumor xenografts treated with the ectopic ATP synthase inhibitor citreoviridinPLoS One8(8),1-19(2013)
