Phensuximide
Cat. No.：YN482066
CAS No. ：86-34-0
| 产品名称: | Phensuximide |
| CAS No.: | 86-34-0 |
| Chemical Name: | 1-methyl-3-phenyl-2,5-pyrrolidinedione |
| Synonyms: | Phensuximide; Succitimal; Milontin; Lifene; Phenylsuximide; Epimid; phensuximide, (±)-isomer; |
| 分子量: | 189.21 |
| 分子式: | C₁₁H₁₁NO₂ |
| SMILES: | O=C(C(C1=CC=CC=C1)C2)N(C)C2=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Phensuximide 是一种琥珀酰亚胺类抗癫痫 (antiepileptic) 和抗惊厥 (anticonvulsant) 试剂。Phensuximide 可以抑制去极化脑组织中 cyclic AMP 和 cyclic GMP 的积累。在动物模型中，Phensuximide 可用于癫痫研究的相关研究。 |
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Kornet, M.J., Crider, A.M., and Magarian, E.O.Potential long-acting anticonvulsants. 1. Synthesis and activity of succinimides containing an alkylating group at the 2 positionJ. Med. Chem.20(3),405-409(1977)
Rankin, G.O., Cressey-Veneziano, K., Wang, R.T., et al.Urinary tract effects of phensuximide in the Sprague-Dawley and Fischer 344 ratJ. Appl. Toxicol.6(5),349-356(1986)
