Gliquidone
Cat. No.：YN481973
CAS No. ：33342-05-1
规格
价格(RMB)
库存
| 产品名称: | Gliquidone |
| CAS No.: | 33342-05-1 |
| Chemical Name: | N-[(cyclohexylamino)carbonyl]-4-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolinyl)ethyl]-benzenesulfonamide |
| Synonyms: | 格列喹酮; AR-DF 26 |
| 分子量: | 527.63 |
| 分子式: | C₂₇H₃₃N₃O₆S |
| SMILES: | O=S(C1=CC=C(CCN(C(C(C)(C)C2=C3C=C(OC)C=C2)=O)C3=O)C=C1)(NC(NC4CCCCC4)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Gliquidone (AR-DF 26) 是一种磺酰脲类的抗糖尿病药物, 用于研究2型糖尿病。 |
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Liu, S.-Y., Tian, H.M., Liao, D.Q., et al.The effect of gliquidone on KATP channels in pancreatic β-cells, cardiomyocytes, and vascular smooth muscle cellsDiabetes Res. Clin. Pract.109(2),334-339(2015)
Scarsi, M., Podvinec, M., Roth, A., et al.Sulfonylureas and glinides exhibit peroxisome proliferator-activated receptor gamma activity: A combined virtual screening and biological assay approachMol. Pharmacol.71(2),398-406(2015)
García-Martínez, J.A., Villanueva-Peñacarrillo, M.L., Valverde, I., et al.Stimulation of insulin release and potentiation of the insulinotropic action of antidiabetic agents by 1,2,3-tri(methylsuccinyl)glycerol ester in anaesthetized ratsPharmacol. Res.36(5),369-372(1997)
Yanardag, R., Ozsoy-Sacan, O., Orak, H., et al.Protective effects of glurenorm (gliquidone) treatment on the liver injury of experimental diabetesDrug Chem. Toxicol.28(4),483-497(2005)
