Carbetapentane citrate
Cat. No.:YN481952
| 产品名称: | Carbetapentane citrate | 
| CAS No.: | 23142-01-0 | 
| Chemical Name: | 1-phenyl-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester, 2-hydroxy-1,2,3-propanetricarboxylate | 
| Synonyms: | 咳必清; Pentoxyverine citrate | 
| 分子量: | 525.59 | 
| 分子式: | C₂₆H₃₉NO₁₀ | 
| SMILES: | O=C(C1(C2=CC=CC=C2)CCCC1)OCCOCCN(CC)CC.O=C(CC(C(O)=O)(O)CC(O)=O)O | 
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. | 
| 运输: | Room temperature in continental US; may vary elsewhere. | 
| 产品描述: | Carbetapentane柠檬酸盐对咳嗽中枢有选择性抑制作用, 有轻度的阿托品样作用和局麻作用。 | 
| IC50和靶点: | |
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Ganapathy, M.E., Prasad, P.D., Huang, W., et al.Molecular and ligand-binding characterization of the σ-receptor in the Jurkat human T lymphocyte cell lineJ. Pharmacol. Exp. Ther.289(1),251-260(1999)
Brown, C., Fezoui, M., Selig, W.M., et al.Antitussive activity of sigma-1 receptor agonists in the guinea-pigBr. J. Pharmacol.141(2),233-240(2004)
Kim, H.-C., Jhoo, W.-K., Kim, W.-K., et al.Carbetapentane attenuates kainate-induced seizures via σ-1 receptor modulationLife Sci.69(8),915-922(2001)