Succimer
Cat. No.：YN482068
CAS No. ：304-55-2
| 产品名称: | Succimer |
| CAS No.: | 304-55-2 |
| Chemical Name: | (2R,3S)-rel-2,3-dimercapto-butanedioic acid |
| Synonyms: | 二巯基丁二酸; Dimercaptosuccinic acid; DMSA |
| 分子量: | 182.22 |
| 分子式: | C₄H₆O₄S₂ |
| SMILES: | O=C(O)[C@@H](S)[C@@H](S)C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Succimer (Dimercaptosuccinic acid) 是一种广泛用于研究铅中毒的螯合剂。 |
| IC50和靶点: | |
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Aposhian, H.V., Hsu, C.-A., and Hoover, T.D.DL- and meso-dimercaptosuccinic acid: in vitro and in vivo studies with sodium arseniteToxicol. Appl. Pharmacol.69(2),206-213(1983)
Yajima, Y., Kawaguchi, M., Yoshikawa, M., et al.The effects of 2,3-dimercapto-1-propanesulfonic acid (DMPS) and meso-2,3-dimercaptosuccinic acid (DMSA) on the nephrotoxicity in the mouse during repeated cisplatin (CDDP) treatmentsJ. Pharmacol. Sci.134(2),108-115(2017)
Gürer, H., Özgünes, H., Neal, R., et al.Antioxidant effects of N-acetylcysteine and succimer in red blood cells from lead-exposed ratsToxicology128(3),181-189(1998)
Zhang, J., Wang, X.-F., Lu, Z.-B., et al.The effects of meso-2,3-dimercaptosuccinic acid and oligomeric procyanidins on acute lead neurotoxicity in rat hippocampusFree Rad. Biol. Med.37(7),1037-1050(2004)
Stewart, P.W., Blaine, C., Cohen, M., et al.Acute and longer term effects of meso-2,3 dimercaptosuccinic acid (DMSA) on the behavior of lead-exposed and control micePhysiol. Behav.59(4-5),849-855(1996)
